Bio-assay Guided Isolation of α-Glucosidase Inhibitory Constituents from Eclipta alba
نویسندگان
چکیده
منابع مشابه
α-Glucosidase inhibitory constituents from Acanthopanax senticosus harm leaves.
A new triterpene glycoside, 3-O-[(α-L-rhamnopyranosyl)(1→2)]-[β-D-glucuronopyranosyl-6-O-methyl ester]-olean-12-ene-28-olic acid (1) and a new indole alkaloid, 5-methoxy-2-oxoindolin-3-acetic acid methyl ester (5) were isolated from the leaves of Acanthopanax senticosus Harms along with six known compounds. The structures of the new compounds were determined by means of 2D-NMR experiments and c...
متن کاملEnzyme Assay Guided Isolation of an α-Amylase Inhibitor Flavonoid from Vaccinium arctostaphylos Leaves
The management of postprandial hyperglycemia is an important strategy in the control of diabetes mellitus and complications associated with the disease, especially in the diabetes type 2. Therefore, inhibitors of carbohydrate hydrolyzing enzymes can be useful in the treatment of diabetes and medicinal plants can offer an attractive strategy for the purpose. Vaccinium arctostaphylos leaves are c...
متن کاملEnzyme Assay Guided Isolation of an α-Amylase Inhibitor Flavonoid from Vaccinium arctostaphylos Leaves
The management of postprandial hyperglycemia is an important strategy in the control of diabetes mellitus and complications associated with the disease, especially in the diabetes type 2. Therefore, inhibitors of carbohydrate hydrolyzing enzymes can be useful in the treatment of diabetes and medicinal plants can offer an attractive strategy for the purpose. Vaccinium arctostaphylos leaves are c...
متن کاملPhenolic Constituents from Sarcopyramis Nepalensis and Their Α-glucosidase Inhibitory Activity
Background: This study was carried out to fully investigate the phenolic chemical constituents of Sarcopyramis nepalensis and determine their α-glucosidase inhibitory activity. Materials and Methods: S. nepalensis was extracted using the ultrasonic assistant extraction (UAE) method and further fractionated with petroleum ether (PE), chloroform (CHCl3), ethyl acetate (EtOAc) and n-butanol (n-BuO...
متن کاملFlavonoids from Salvia chloroleuca with α-Amylsae and α-Glucosidase Inhibitory Effect
It is believed that the inhibition of carbohydrate hydrolyzing enzymes including α-amylase and α-glucosidase is one of the therapeutic approaches to decrease the postprandial glucose level after a meal, especially in the people with type 2 diabetes. Medicinal plants and their extracts are one of the main sources to find new inhibitors to the enzymes. In our study four flavonoids, namely luteoli...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2012
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1200700807